Archive Issue Details

Archive Issue Details Volume.2 ,Issue . 4

Manuscript Number
IJPRT-2023-11-062

Manuscript Title
Development and Evaluation of In - Situ Nasal Gel of Candesartan Cilexetil

Article Type
Original Research Articles

Author Names

Akash Hole *
Dr. Sandip Kshirsagar
Dhanashree Punde

Abstract
Now a day’s Nasal route is successfully used for the systemic delivery of various drugs like antidiabetic, antidepressants, vitamins and insulin delivery as it avoids first pass metabolism, gastrointestinal irritation, increases the bioavailability and residence time. The large surface area of the nasal mucosa offers a rapid onset of therapeutic effect, potential for direct-to-central nervous system delivery, no first-pass metabolism, and non- invasiveness; all of which may maximize patient conv

Keywords .
Gastrointestinal irritation, Bioavailability, first-pass metabolism, Mucoadhesive

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