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Abstract
Now a day’s Nasal route is successfully used for the systemic delivery of various drugs like antidiabetic, antidepressants, vitamins and insulin delivery as it avoids first pass metabolism, gastrointestinal irritation, increases the bioavailability and residence time. The large surface area of the nasal mucosa offers a rapid onset of therapeutic effect, potential for direct-to-central nervous system delivery, no first-pass metabolism, and non- invasiveness; all of which may maximize patient conv

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