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Abstract
In this study, it was intended to formulate floating Mucoadhesive tablets containing Acebutolol hydrochloride, an antihypertensive agent, to release the drug for a prolonged period of time in the upper part of the gastrointestinal tract in order to first-pass metabolism for improvement in bioavailability, to decrease the frequency of dosing, and to improve patient compliance. The effects of several polymers, including HPMC K4M and Carbopol 934, on the Mucoadhesive strength and release kinetics o

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