Archive Issue Details

Archive Issue Details Volume.1 ,Issue . 4

Manuscript Number
IJPRT 2022-10-008

Manuscript Title
Enhancement of Dissolution Profile of Torsemide by Solid Dispersion Technique

Article Type
Original Research Articles

Author Names

Tejaswini Neve *
Pranali Deshmukh

Abstract
The objective of the present study was to improve the aqueous solubility and dissolution characteristics of the loop diuretic Torsemide (TOR); a class IV drug in the Biopharmaceutical Classification System (BCS) using solid dispersion technique. Solid TOR dispersions at various ratios were prepared using solvent evaporation and kneading techniques with the hydrophilic carrier polyvinylpyrrolidone K-90 (PVP-K30). The generated solid dispersions underwent evaluations for drug content, yield in ter

Keywords .
K-90, Torsemide, Dissolution

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