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Abstract
A stress response is activated when an uncomfortable stimulus is generated from an external environment or from within the organism, this activation leads to stimulation of the hypothalamic region of the brain which further stimulates and activates the pituitary gland, which leads to stimulation of the adrenal glands and release of stress hormones in the blood. This chain activation of the Hypothalamus, pituitary gland, and adrenal glands is the key step in the generation of the stress response.

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