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Archive Issue Details
Volume.2 ,Issue . 3
Manuscript Number
IJPRT-2023-08-025
Manuscript Title
Stability Indicating Method Development and Validation of Ziprasidone by using RP-HPLC Method
Article Type
Original Research Articles
Author Names
Patil Mamta *
Javesh Patil
Abstract
A new simple, sensitive and stability indicating RP-HPLC method for the determination of Ziprasidone in pharmaceutical dosage form was developed. Chromatographic separation was carried on Reverse Phase C18 (Cosmosil) column (symmetry 250x4.6mm;5µm) with a mobile phase composed of acetonitrile and 0.05% (OPA) water (90:10 v/v) having pH 3.0 at an absorption maxima 318nm. The analysis of the drug was carried out on Agilent Tech. Gradient System with Auto injector DAD Detector. Equipped with Revers
Keywords .
Stability indicating, RP-HPLC, Ziprasidone, Cosmosil, dosage form.
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